China OEM Bacterial Endotoxin Test Principle - Beta-glucans Blocker for Blocking Beta Glucan Pathway – Bioendo

Beta-glucans Blocker for Blocking Beta Glucan Pathway

1. Product information

There are two pathway in limulus amoebocyte lysate lal reagent, factor C pathway is specific to endotoxin and factor G pathway is specific to(1,3)- β-D-Glucans. If the test sample contains β-1,3-Glucans, the limulus test (Endotoxin test ) will have interferences. β-G-Blocker blocks the reactivity of LAL to β-1,3-Glucans，conferring increased endotoxin specificity to the LAL test. If the test samples containsβ-1,3-Glucan, such as cellulose, using beta-glucans blocker would be a good idea to block the β-1,3-Glucan interference to endotoxin and LAL reagent reaction.

2. Product parameter

Endotoxin level less than 0.005EU/ml

3. Product features and application

Substitute LAL Reagent Water to reconstitute LAL reagent, blocks the beta-glucan mediates factor G pathway and insure the LAL reagent only reacts to endotoxin. For the test samples that has the (1,3)- β-D-Glucan contamination.

Product Condition

The sensitivity of Lyophilized Amebocyte Lysate and potency of Control Standard Endotoxin are assayed against USP Reference Standard Endotoxin. The Lyophilized Amebocyte Lysate reagent kits come with product instruction, Certificate of Analysis.